CONTENT VALIDATION AND DISCLOSURES

Research To Practice is committed to providing its participants with high-quality, unbiased and state-of-the-art education. We assess potential conflicts of interest with faculty, planners and managers of CME activities. Real or apparent conflicts of interest are identified and resolved by a peer review content validation process. The content of each activity is reviewed by both a member of the scientific staff and an external independent reviewer for fair balance, scientific objectivity of studies referenced and patient care recommendations.

The scientific staff and consultants for Research To Practice are involved in the development and review of content for educational activities and report the following real or apparent conflicts of interest, either current or within the past 12 months, for themselves (or their spouses/partners) that have been resolved through a peer review process: John Brebner, Richard Kaderman, PhD, Neil Love, MD, Douglas Paley, Margaret Peng, Lilliam Sklaver Poltorack, PharmD, Ginelle Suarez, Chris Thomson, MD, MS, Erin Wall and Kathryn Ault Ziel, PhD — no real or apparent conflicts of interest to report; Aviva Asnis-Alibozek, PA-C, MPAS — salary: AstraZeneca Pharmaceuticals LP; shareholder of AstraZeneca Pharmaceuticals LP; Sally Bogert, RNC, WHCNP — shareholder of Amgen Inc and Genentech BioOncology. Research To Practice receives education grants from Abraxis BioScience, Amgen Inc, AstraZeneca Pharmaceuticals LP, Bayer Pharmaceuticals Corporation/Onyx Pharmaceuticals Inc, Biogen Idec, Genentech BioOncology/OSI Pharmaceuticals Inc, Genomic Health Inc, GPC Biotech, Roche Laboratories Inc and Sanofi-Aventis, who have no influence on the content development of our educational activities.

In addition, the following faculty (and their spouses/partners) have reported real or apparent conflicts of interest that have been resolved through a peer review process:

Dr Miller — Consulting Fees: Genentech BioOncology; Contracted Research: Genentech BioOncology, Sanofi-Aventis.

Dr Winer — No financial interests or affiliations to disclose.

Dr Jones — Consulting Fees: Pfizer Inc, Sanofi-Aventis; Fees for Non-CME Services Received Directly from Commercial Interest or Their Agents: AstraZeneca Pharmaceuticals LP, Genentech BioOncology, GlaxoSmithKline, Pfizer Inc, Sanofi-Aventis.

Dr Saltz — Consulting Fees: Merck and Company Inc; Contracted Research: Amgen Inc, Bayer Pharmaceuticals Corporation, Bristol-Myers Squibb Company, Genentech BioOncology, ImClone Systems, Pfizer Inc, Roche Laboratories Inc, Taiho Pharmaceutical Co.

Dr Venook — Contracted Research: Amgen Inc, Genentech BioOncology, GlaxoSmithKline, Novartis Pharmaceuticals Corporation, Pfizer Inc.

Dr Kahl — Consulting Fees: Cephalon Inc, Genentech BioOncology.

Dr Kim — Consulting Fees: AstraZeneca Pharmaceuticals LP, Eli Lilly and Company, Genentech BioOncology, ImClone Systems, OSI Pharmaceuticals Inc, Sanofi-Aventis; Fees for Non-CME Services Received Directly from Commercial Interest or Their Agents: Eli Lilly and Company, Genentech BioOncology, Sanofi-Aventis; Contracted Research: AstraZeneca Pharmaceuticals LP, Eli Lilly and Company, Genentech BioOncology, ImClone Systems, OSI Pharmaceuticals Inc, Sanofi-Aventis.

Dr Lilenbaum — Consulting Fees: AstraZeneca Pharmaceuticals LP, Genentech BioOncology, Sanofi-Aventis.

Dr Vogelzang — Consulting Fees: Bayer Pharmaceuticals Corporation, Cougar Biotechnology Inc, Dendreon, Eli Lilly and Company, GPC Biotech, Hana Biosciences, Merck KGaA, Pfizer Inc, Sanofi-Aventis; Contracted Research: Argos, Bayer Pharmaceuticals Corporation, Dendreon, Genentech BioOncology, GPC Biotech, MannKind Corporation, Millennix Oncology, Novacea Inc, Novartis Pharmaceuticals Corporation, Pfizer Inc, Sanofi-Aventis, US Department of Defense, US Department of Energy, Wilex AG.

Dr Bukowski — Consulting Fees: Bayer Pharmaceuticals Corporation, Bristol-Myers Squibb Company, Genentech BioOncology, Novartis Pharmaceuticals Corporation, Onyx Pharmaceuticals, Pfizer Inc, Wyeth; Fees for Non- CME Services Received Directly from Commercial Interest or Their Agents: Onyx Pharmaceuticals, Pfizer Inc; Contracted Research: Bayer Pharmaceuticals Corporation, Bristol-Myers Squibb Company, Genentech BioOncology, Pfizer Inc, Wyeth.

This educational activity contains discussion of published and/or investigational uses of agents that are not indicated by the Food and Drug Administration. Research To Practice does not recommend the use of any agent outside of the labeled indications. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings. The opinions expressed are those of the presenters and are not to be construed as those of the publisher or grantors.